Lipids modulate the conformational dynamics of a secondary multidrug transporter

Abstract

Direct interactions with lipids have emerged as key determinants of the folding, structure and function of membrane proteins, but an understanding of how lipids modulate protein dynamics is still lacking. Here, we systematically explored the effects of lipids on the conformational dynamics of the proton-powered multidrug transporter LmrP from Lactococcus… (More)
DOI: 10.1038/nsmb.3262

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