Lipidomics of Mesenchymal Stromal Cells: Understanding the Adaptation of Phospholipid Profile in Response to Pro‐Inflammatory Cytokines

@article{Campos2016LipidomicsOM,
  title={Lipidomics of Mesenchymal Stromal Cells: Understanding the Adaptation of Phospholipid Profile in Response to Pro‐Inflammatory Cytokines},
  author={Ana Margarida Ferreira Campos and Elisabete A Maciel and Ana S P Moreira and Bebiana C. Sousa and T{\^a}nia Melo and Pedro Domingues and Liliana Curado and Br{\'i}gida Antunes and Maria do Ros{\'a}rio Domingues and Francisco Santos},
  journal={Journal of Cellular Physiology},
  year={2016},
  volume={231}
}
Mesenchymal stromal cells (MSCs) present anti‐inflammatory properties and are being used with great success as treatment for inflammatory and autoimmune diseases. In clinical applications MSCs are subjected to a strong pro‐inflammatory environment, essential to their immunosuppressive action. Despite the wide clinical use of these cells, how MSCs exert their effect remains unclear. Several lipids are known to be involved in cell's signaling and modulation of cellular functions. The aim of this… Expand
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