Lipid segregation and IgE receptor signaling: a decade of progress.

@article{Holowka2005LipidSA,
  title={Lipid segregation and IgE receptor signaling: a decade of progress.},
  author={David A. Holowka and Julie A. Gosse and Adam T. Hammond and Xuemei Han and Prabuddha Sengupta and Norah L. Smith and Alice Wagenknecht-Wiesner and Min Wu and Ryan M Young and B. Baird},
  journal={Biochimica et biophysica acta},
  year={2005},
  volume={1746 3},
  pages={252-9}
}
Recent work to characterize the roles of lipid segregation in IgE receptor signaling has revealed a mechanism by which segregation of liquid ordered regions from disordered regions of the plasma membrane results in protection of the Src family kinase Lyn from inactivating dephosphorylation by a transmembrane tyrosine phosphatase. Antigen-mediated… CONTINUE READING