Lipid regulation of CTP: phosphocholine cytidylyltransferase: electrostatic, hydrophobic, and synergistic interactions of anionic phospholipids and diacylglycerol.

@article{Arnold1996LipidRO,
  title={Lipid regulation of CTP: phosphocholine cytidylyltransferase: electrostatic, hydrophobic, and synergistic interactions of anionic phospholipids and diacylglycerol.},
  author={Robert S. Arnold and Rosemary B. Cornell},
  journal={Biochemistry},
  year={1996},
  volume={35 30},
  pages={9917-24}
}
The contributions of electrostatic and hydrophobic interactions in the activation of cytidylyl-transferase (CT) by various negatively charged lipids were analyzed using small unilamellar or multilamellar vesicles (SUVs or MLVs). The activation of CT by SUVs containing increasing mole percentages of anionic phospholipids varied in proportion to the net charge associated with the polar head group, suggesting an electrostatic component to the activation. However, increasing ionic strength to… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 17 extracted citations

Topological regulation of lipid balance in cells.

Annual review of biochemistry • 2014
View 8 Excerpts
Highly Influenced

Similar Papers

Loading similar papers…