Lipid rafts mediate the interaction between myelin-associated glycoprotein (MAG) on myelin and MAG-receptors on neurons.

@article{Vinson2003LipidRM,
  title={Lipid rafts mediate the interaction between myelin-associated glycoprotein (MAG) on myelin and MAG-receptors on neurons.},
  author={Mary Vinson and Oliver Rausch and Peter R. Maycox and Rabinder K Prinjha and Debra Chapman and Rachel Morrow and Alex J. Harper and Colin Dingwall and Frank S. Walsh and Stephen A. Burbidge and David R. Riddell},
  journal={Molecular and cellular neurosciences},
  year={2003},
  volume={22 3},
  pages={344-52}
}
The interaction between myelin-associated glycoprotein (MAG), expressed at the periaxonal membrane of myelin, and receptors on neurons initiates a bidirectional signalling system that results in inhibition of neurite outgrowth and maintenance of myelin integrity. We show that this involves a lipid-raft to lipid-raft interaction on opposing cell membranes. MAG is exclusively located in low buoyancy Lubrol WX-insoluble membrane fractions isolated from whole brain, primary oligodendrocytes, or MAG… CONTINUE READING
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