Lipid rafts in health and disease.

  title={Lipid rafts in health and disease.},
  author={Vera Michel and Marica Bakovic},
  journal={Biology of the cell},
  volume={99 3},
Lipid rafts are sphingolipid- and cholesterol-rich domains of the plasma membrane which contain a variety of signalling and transport proteins. Different subtypes of lipid rafts can be distinguished according to their protein and lipid composition. Caveolae are types of rafts that are rich in proteins of the caveolin family (caveolin-1, -2 and -3) which present a distinct signalling platform. The importance of lipid raft signalling in the pathogenesis of a variety of conditions, such as… CONTINUE READING