Lipid rafts and caveolae as portals for endocytosis: new insights and common mechanisms.

  title={Lipid rafts and caveolae as portals for endocytosis: new insights and common mechanisms.},
  author={Robert G. Parton and Ayanthi A Richards},
  volume={4 11},
Clathrin-coated pits and caveolae are two of the most recognizable features of the plasma membrane of mammalian cells. While our understanding of the machinery regulating and driving clathrin-coated pit-mediated endocytosis has progressed dramatically, including the elucidation of the structure of individual components and partial in vitro reconstitution, the role of caveolae as alternative endocytic carriers still remains elusive 50 years after their discovery. However, recent work has started… CONTINUE READING

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