Lipid rafts: contentious only from simplistic standpoints

  title={Lipid rafts: contentious only from simplistic standpoints},
  author={John F Hancock},
  journal={Nature Reviews Molecular Cell Biology},
The hypothesis that lipid rafts exist in plasma membranes and have crucial biological functions remains controversial. The lateral heterogeneity of proteins in the plasma membrane is undisputed, but the contribution of cholesterol-dependent lipid assemblies to this complex, non-random organization promotes vigorous debate. In the light of recent studies with model membranes, computational modelling and innovative cell biology, I propose an updated model of lipid rafts that readily accommodates… CONTINUE READING
Highly Influential
This paper has highly influenced 22 other papers. REVIEW HIGHLY INFLUENTIAL CITATIONS


Publications citing this paper.
Showing 1-10 of 317 extracted citations


Publications referenced by this paper.
Showing 1-10 of 81 references

Agrobacterium tumefaciens oncogenic suppressors inhibit TDNA and VirE 2 protein substrate binding to the VirD 4 coupling protein

  • E. Cascales, K. Atmakuri, Z. Liu, A. N. Binns, P. J. Christie
  • J . Cell Biol .
  • 2006

Similar Papers

Loading similar papers…