Lipid raft-dependent targeting of the influenza A virus nucleoprotein to the apical plasma membrane.

@article{Carrasco2004LipidRT,
  title={Lipid raft-dependent targeting of the influenza A virus nucleoprotein to the apical plasma membrane.},
  author={Marlene Carrasco and Maria Jo{\~a}o Amorim and Paul Digard},
  journal={Traffic},
  year={2004},
  volume={5 12},
  pages={979-92}
}
Influenza virus acquires a lipid raft-containing envelope by budding from the apical surface of epithelial cells. Polarised budding involves specific sorting of the viral membrane proteins, but little is known about trafficking of the internal virion components. We show that during the later stages of virus infection, influenza nucleoprotein (NP) and polymerase (the protein components of genomic ribonucleoproteins) localised to apical but not lateral or basolateral membranes, even in cell types… CONTINUE READING
43 Citations
0 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 43 extracted citations

Similar Papers

Loading similar papers…