Lipid phase separation in phospholipid bilayers and monolayers modeling the plasma membrane.

@article{Shaikh2001LipidPS,
  title={Lipid phase separation in phospholipid bilayers and monolayers modeling the plasma membrane.},
  author={Saame Raza Shaikh and Alfred C Dumaual and Laura J. Jenski and William Stillwell},
  journal={Biochimica et biophysica acta},
  year={2001},
  volume={1512 2},
  pages={317-28}
}
It is postulated that biological membrane lipids are heterogeneously distributed into lipid microdomains. Recent evidence indicates that docosahexaenoic acid-containing phospholipids may be involved in biologically important lipid phase separations. Here we investigate the elastic and thermal properties of a model plasma membrane composed of egg sphingomyelin (SM), cholesterol and 1-stearoyl-2-docosahexaenoyl-sn-glycerophosphoethanolamine (SDPE). Two techniques are employed, pressure-area… CONTINUE READING
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