Lipid peroxidation induced by bolesatine, a toxin ofBoletus satanas: Implication in m5dC variation in Vero cells related to inhibition of cell growth

@article{Ennamany1995LipidPI,
  title={Lipid peroxidation induced by bolesatine, a toxin ofBoletus satanas: Implication in m5dC variation in Vero cells related to inhibition of cell growth},
  author={Rachid Ennamany and S. Marzetto and Dominique Saboureau and Edmond Eku{\'e} Creppy},
  journal={Cell Biology and Toxicology},
  year={1995},
  volume={11},
  pages={347-354}
}
Bolesatine, a glycoprotein fromBoletus satanas Lenz, has previously been shown to be mitogenic in rat and human lymphocytes at very low concentrations, whereas higher concentrations inhibited protein synthesisin vitro and in severalin vivo systems. The low concentrations (1–10 ng/ml) of bolesatine were shown to activate protein kinase C (PKC)in vitro (cell-free system) and in Vero cells. In the same time, Vero cells significantly proliferated when incubated with bolesatine concentrations… CONTINUE READING