Lipid peroxidation in diabetes mellitus.

  title={Lipid peroxidation in diabetes mellitus.},
  author={Giovanni Dav{\'i} and A. Ruiz Falc{\'o} and Carlo Patrono},
  journal={Antioxidants & redox signaling},
  volume={7 1-2},
There is considerable evidence that hyperglycemia represents the main cause of complications of diabetes mellitus (DM), and oxidative stress resulting from increased generation of reactive oxygen species plays a crucial role in their pathogenesis. In fact, in the absence of an appropriate response from endogenous antioxidant mechanisms, the redox imbalance causes the activation of stress-sensitive intracellular signaling pathways. The latter play a key role in the development of late… CONTINUE READING