Lipid peroxidation in alcoholic liver disease in humans.

  title={Lipid peroxidation in alcoholic liver disease in humans.},
  author={T. Suematsu and Takuro Matsumura and Nobuhiro Sato and Takeshi Miyamoto and Tomonori Ooka and Takenobu Kamada and Hiroshi Abe},
  journal={Alcoholism, clinical and experimental research},
  volume={5 3},
The lipoperoxide level in liver as well as serum in alcoholic patients was measured by using the thiobarbituric acid method. Heavy drinkers with deposition of fat in liver had a significantly (p less than 0.001) higher level of hepatic lipoperoxide examined in about 7 days after abstinence than did nonalcoholic individuals with histologically normal liver. Of these heavy drinkers, cases with a remarkably high level of liver lipoperoxide showed a high incidence of hepatic cell necrosis. The… CONTINUE READING
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