Lipid peroxidation generates biologically active phospholipids including oxidatively N-modified phospholipids.

@article{Davies2014LipidPG,
  title={Lipid peroxidation generates biologically active phospholipids including oxidatively N-modified phospholipids.},
  author={Sean S Davies and Lilu Guo},
  journal={Chemistry and physics of lipids},
  year={2014},
  volume={181},
  pages={1-33}
}
Peroxidation of membranes and lipoproteins converts "inert" phospholipids into a plethora of oxidatively modified phospholipids (oxPL) that can act as signaling molecules. In this review, we will discuss four major classes of oxPL: mildly oxygenated phospholipids, phospholipids with oxidatively truncated acyl chains, phospholipids with cyclized acyl chains, and phospholipids that have been oxidatively N-modified on their headgroups by reactive lipid species. For each class of oxPL we will… CONTINUE READING

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