Lipid peroxidation and apoptotic response in rat brain areas induced by long‐term administration of nandrolone: the mutual crosstalk between ROS and NF‐kB

@inproceedings{Turillazzi2016LipidPA,
  title={Lipid peroxidation and apoptotic response in rat brain areas induced by long‐term administration of nandrolone: the mutual crosstalk between ROS and NF‐kB
},
  author={Emanuela Turillazzi and Margherita Neri and Daniela Cerretani and Santina Cantatore and Paola Frati and Laura Moltoni and Francesco Paolo Busard{\`o} and Cristoforo Pomara and Irene Riezzo and Vittorio Fineschi},
  booktitle={Journal of cellular and molecular medicine},
  year={2016}
}
The aim of this study was to evaluate the played by oxidative stress in the apoptotic response in different brain areas of rats chronically treated with supra-physiological doses of nandrolone decanoate (ND). Immunohistochemical study and Western blot analysis were performed to evaluate cells' apoptosis and to measure the effects of expression of specific mediators, such as NF-κB (nuclear factor kappa-light-chain-enhancer of activated B cells), Bcl-2 (B-cell lymphoma 2), SMAC/DIABLO (second… CONTINUE READING