Lipid peroxidation, reactive oxygen species and antioxidative factors in the pathogenesis of gastric mucosal lesions and mechanism of protection against oxidative stress - induced gastric injury.

@article{Kwiecie2014LipidPR,
  title={Lipid peroxidation, reactive oxygen species and antioxidative factors in the pathogenesis of gastric mucosal lesions and mechanism of protection against oxidative stress - induced gastric injury.},
  author={Sławomir Kwiecień and Katarzyna Jasnos and Marcin Magierowski and Zbigniew Śliwowski and Robert Pajdo and Bartosz Brzozowski and Tomasz H Mach and Dagmara W{\'o}jcik and Tomasz Brzozowski},
  journal={Journal of physiology and pharmacology : an official journal of the Polish Physiological Society},
  year={2014},
  volume={65 5},
  pages={613-22}
}
The gastric mucosa plays an important role in the physiological function of the stomach. This mucosa acts as gastric barrier, which protects deeper located cells against the detrimental action of the gastric secretory components, such as acid and pepsin. Integrity of the gastric mucosa depends upon a variety of factors, such as maintenance of microcirculation, mucus-alkaline secretion and activity of the antioxidizing factors. The pathogenesis of gastric mucosal damage includes reactive oxygen… CONTINUE READING