Lipid metabolism in long-lived families: the Leiden Longevity Study

  title={Lipid metabolism in long-lived families: the Leiden Longevity Study},
  author={Anika A. M. Vaarhorst and Marian Beekman and Eka H. D. Suchiman and Diana van Heemst and Jeanine J. Houwing-Duistermaat and Rudi G J Westendorp and Pieternella E Slagboom and Bastiaan T Heijmans},
Mechanisms underlying the variation in human life expectancy are largely unknown, but lipid metabolism and especially lipoprotein size was suggested to play an important role in longevity. We have performed comprehensive lipid phenotyping in the Leiden Longevity Study (LLS). By applying multiple logistic regression analysis we tested for the first time the effects of parameters in lipid metabolism (i.e., classical serum lipids, lipoprotein particle sizes, and apolipoprotein E levels) on… CONTINUE READING


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