Lipid-mediated PX-BAR domain recruitment couples local membrane constriction to endocytic vesicle fission

@inproceedings{Schneberg2017LipidmediatedPD,
  title={Lipid-mediated PX-BAR domain recruitment couples local membrane constriction to endocytic vesicle fission},
  author={Johannes Sch{\"o}neberg and Martin J Lehmann and Alexander Ullrich and York Posor and Wen-Ting Lo and Gregor Lichtner and Jan Schmoranzer and Volker Haucke and Frank No{\'e}},
  booktitle={Nature communications},
  year={2017}
}
Clathrin-mediated endocytosis (CME) involves membrane-associated scaffolds of the bin-amphiphysin-rvs (BAR) domain protein family as well as the GTPase dynamin, and is accompanied and perhaps triggered by changes in local lipid composition. How protein recruitment, scaffold assembly and membrane deformation is spatiotemporally controlled and coupled to… CONTINUE READING