Lipid-lowering and antioxidative activities of 3,4-di(OH)-cinnamate and 3,4-di(OH)-hydrocinnamate in cholesterol-fed rats.

@article{Lee2001LipidloweringAA,
  title={Lipid-lowering and antioxidative activities of 3,4-di(OH)-cinnamate and 3,4-di(OH)-hydrocinnamate in cholesterol-fed rats.},
  author={J. S. H. Lee and Myoung Su Choi and Seon-min Jeon and Tae-Sook Jeong and Y. B. Park and M. K. Lee and Song Hae Bok},
  journal={Clinica chimica acta; international journal of clinical chemistry},
  year={2001},
  volume={314 1-2},
  pages={
          221-9
        }
}
  • J. Lee, M. Choi, S. Bok
  • Published 1 December 2001
  • Biology
  • Clinica chimica acta; international journal of clinical chemistry
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35 Citations

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Effect of 3,4‐di(OH)‐cinnamate synthetic derivative on plasma and hepatic cholesterol level and antioxidant enzyme activities in high cholesterol‐fed rats
TLDR
Results suggest that SL‐1063, a synthetic derivative of 3,4‐di(OH)‐cinnamate, is effective in lowering the plasma lipids and improving the antioxidant enzyme system.
Hypocholesterolemic and antioxidant properties of 3-(4-hydroxyl)propanoic acid derivatives in high-cholesterol fed rats.
4-Hydroxycinnamate Lowers Plasma and Hepatic Lipids without Changing Antioxidant Enzyme Activities
TLDR
Results indicate that 4-(OH)-C was effective in lowering the plasma cholesterol and hepatic lipids in rats fed a high-cholesterol diet.
Anticholesterolemic effect of 3,4-di(OH)-phenylpropionic amides in high-cholesterol fed rats.
Cinnamate supplementation enhances hepatic lipid metabolism and antioxidant defense systems in high cholesterol-fed rats.
TLDR
Dietary cinnamate inhibits hepatic HMG-CoA reductase activity, resulting in lower hepatic cholesterol content, and suppresses lipid peroxidation via enhancement of hepatic antioxidant enzyme activities.
Lipid‐lowering efficacy of 3,4‐di(OH)‐phenylpropionic L‐leucine in high‐cholesterol fed rats
TLDR
Results indicate that PPLA, a leucine‐attached version of HC, exhibited a similar significant hypocholesterolemic effect to HC in rats fed a high‐cholesterol diet.
Synthesis of cinnamic acid derivatives and their inhibitory effects on LDL-oxidation, acyl-CoA:cholesterol acyltransferase-1 and -2 activity, and decrease of HDL-particle size.
Lipid-lowering efficacy of hesperetin metabolites in high-cholesterol fed rats.
Attenuation of Atherosclerosis by 3,4-Dihydroxy- Hydrocinnamic Acid in Rabbits by Partial Inhibition of ACAT
TLDR
Results indicate that 3,4-DHHCA had antiatherogenic effects in rabbits, possibly by partial inhibition of ACAT.
Hypocholesterolemic effects of phenolic-rich extracts of Chemlali olive cultivar in rats fed a cholesterol-rich diet.
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References

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