Lipid intermediates in membrane fusion: formation, structure, and decay of hemifusion diaphragm.

@article{Kozlovsky2002LipidII,
  title={Lipid intermediates in membrane fusion: formation, structure, and decay of hemifusion diaphragm.},
  author={Yonathan Kozlovsky and Leonid V. Chernomordik and Michael M. Kozlov},
  journal={Biophysical journal},
  year={2002},
  volume={83 5},
  pages={2634-51}
}
Lipid bilayer fusion is thought to involve formation of a local hemifusion connection, referred to as a fusion stalk. The subsequent fusion stages leading to the opening of a fusion pore remain unknown. The earliest fusion pore could represent a bilayer connection between the membranes and could be formed directly from the stalk. Alternatively, fusion pore can form in a single bilayer, referred to as hemifusion diaphragm (HD), generated by stalk expansion. To analyze the plausibility of stalk… CONTINUE READING

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