Lipid interaction of alpha-synuclein during the metal-catalyzed oxidation in the presence of Cu2+ and H2O2.

@article{Lee2003LipidIO,
  title={Lipid interaction of alpha-synuclein during the metal-catalyzed oxidation in the presence of Cu2+ and H2O2.},
  author={Eui-Nam Lee and Sun-young Lee and Daekyun Lee and Jongsun Kim and Seung R Paik},
  journal={Journal of neurochemistry},
  year={2003},
  volume={84 5},
  pages={1128-42}
}
Alpha-synuclein co-exists with lipids in the Lewy bodies, a pathological hallmark of Parkinson's disease. Molecular interaction between alpha-synuclein and lipids has been examined by observing lipid-induced protein self-oligomerization in the presence of a chemical coupling reagent of N-(ethoxycarbonyl)-2-ethoxy-1,2-dihydroquinoline. Lipids such as… CONTINUE READING