Lipid hydroperoxides initiate the autoxidation of sulfite with concomitant production of superoxide.

@article{Brestel1986LipidHI,
  title={Lipid hydroperoxides initiate the autoxidation of sulfite with concomitant production of superoxide.},
  author={Eric P. Brestel and W F Petrone and Richard Alan Cohen},
  journal={Journal of free radicals in biology & medicine},
  year={1986},
  volume={2 3},
  pages={219-25}
}
The inhalation of SO2 or the ingestion of beverages or food containing sulfite as a preservative has been associated with exacerbations of obstructive pulmonary disease. In this study it is demonstrated that 15-HPETE, a likely component of the lung's inflammatory response, can initiate the autoxidation of sulfite. Since 1 mol of 15-HPETE can initiate the consumption of 3 mol of oxygen and 6 mol of sulfite, it is likely that a free radical chain mechanism is operative. Direct evidence for the… CONTINUE READING