Lipid hydroperoxide induced oxidative stress damage and antioxidant enzyme response in Caco-2 human colon cells.

@article{Wijeratne2006LipidHI,
  title={Lipid hydroperoxide induced oxidative stress damage and antioxidant enzyme response in Caco-2 human colon cells.},
  author={Subhashinee S. K. Wijeratne and Susan L. Cuppett},
  journal={Journal of agricultural and food chemistry},
  year={2006},
  volume={54 12},
  pages={
          4476-81
        }
}
It has been demonstrated that reactive oxygen species, free radicals, and oxidative products, such as lipid hydroperoxides, participate in tissue injuries and in the onset and progression of degenerative diseases in humans. Studies were conducted using Caco-2 colon carcinoma cells to evaluate cellular damage caused by exposing cells for 30 min to oleic acid hydroperoxides (OAHPx) at concentrations varying from 0 to 25 microM. Cell membrane damage and DNA damage were significantly high even at… CONTINUE READING
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