Lipid efflux by the ATP-binding cassette transporters ABCA1 and ABCG1.

@article{Cavelier2006LipidEB,
  title={Lipid efflux by the ATP-binding cassette transporters ABCA1 and ABCG1.},
  author={Clara Cavelier and Iris Lorenzi and Lucia Rohrer and Arnold von Eckardstein},
  journal={Biochimica et biophysica acta},
  year={2006},
  volume={1761 7},
  pages={655-66}
}
Plasma levels of high-density lipoproteins (HDL) and apolipoprotein A-I (apoA-I) are inversely correlated with the risk of cardiovascular disease. One major atheroprotective mechanism of HDL and apoA-I is their role in reverse cholesterol transport, i.e., the transport of excess cholesterol from foam cells to the liver for secretion. The ATP-binding… CONTINUE READING