Lipid droplets and hepatitis C virus infection.

@article{McLauchlan2009LipidDA,
  title={Lipid droplets and hepatitis C virus infection.},
  author={J. McLauchlan},
  journal={Biochimica et biophysica acta},
  year={2009},
  volume={1791 6},
  pages={552-9}
}
Lipid droplets play an important part in the life cycle of hepatitis C virus and also are markers for steatosis, which is a common condition that arises during infection. These storage organelles are targeted by the viral core protein, which forms the capsid shell. Attachment of core to lipid droplets requires a C-terminal domain within the protein that is highly conserved between different virus isolates. In infected cells, the presence of core on lipid droplets creates loci that contain viral… CONTINUE READING
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