Lipid droplets and cellular lipid metabolism.

  title={Lipid droplets and cellular lipid metabolism.},
  author={Tobias C. Walther and Robert V Farese},
  journal={Annual review of biochemistry},
Among organelles, lipid droplets (LDs) uniquely constitute a hydrophobic phase in the aqueous environment of the cytosol. Their hydrophobic core of neutral lipids stores metabolic energy and membrane components, making LDs hubs for lipid metabolism. In addition, LDs are implicated in a number of other cellular functions, ranging from protein storage and degradation to viral replication. These processes are functionally linked to many physiological and pathological conditions, including obesity… CONTINUE READING
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