Lipid domain separation, bilayer thickening and pearling induced by the cell penetrating peptide penetratin.

@article{Lamazire2010LipidDS,
  title={Lipid domain separation, bilayer thickening and pearling induced by the cell penetrating peptide penetratin.},
  author={Antonin Lamazi{\`e}re and Ofelia Maniti and Claude Wolf and Olivier Lambert and G{\'e}rard Chassaing and Germain Trugnan and Jesus Ayala-Sanmartin},
  journal={Biochimica et biophysica acta},
  year={2010},
  volume={1798 12},
  pages={2223-30}
}
Protein membrane transduction domains are able to translocate through cell membranes. This capacity resulted in new concepts on cell communication and in the design of vectors for internalization of active molecules into cells. Penetratin crosses the plasma membrane by a receptor and metabolic energy-independent mechanism which is at present unknown. A better knowledge of its interaction with phospholipids will help to understand the molecular mechanisms of cell penetration. Here, we… CONTINUE READING