Lipid domain–dependent regulation of single-cell wound repair

@inproceedings{Vaughan2014LipidDR,
  title={Lipid domain–dependent regulation of single-cell wound repair},
  author={Emily M. Vaughan and Jae-Sung You and Hoi-Ying Elsie Yu and Amber Lasek and Nicolas Vitale and Troy A Hornberger and William M. Bement},
  booktitle={Molecular biology of the cell},
  year={2014}
}
After damage, cells reseal their plasma membrane and repair the underlying cortical cytoskeleton. Although many different proteins have been implicated in cell repair, the potential role of specific lipids has not been explored. Here we report that cell damage elicits rapid formation of spatially organized lipid domains around the damage site, with… CONTINUE READING