Lipid-dependent bidirectional traffic of apolipoprotein B in polarized enterocytes.

  title={Lipid-dependent bidirectional traffic of apolipoprotein B in polarized enterocytes.},
  author={Etienne Morel and Sylvie Demignot and Danielle Ch{\^a}teau and Jean Chambaz and Monique Rousset and François Delers},
  journal={Molecular biology of the cell},
  volume={15 1},
Enterocytes are highly polarized cells that transfer nutrients across the intestinal epithelium from the apical to the basolateral pole. Apolipoprotein B (apoB) is a secretory protein that plays a key role in the transepithelial transport of dietary fatty acids as triacylglycerol. The evaluation of the control of apoB traffic by lipids is therefore of particular interest. To get a dynamic insight into this process, we used the enterocytic Caco-2 cells cultured on microporous filters, a system… CONTINUE READING

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