Lipid compartmentalization in the endosome system.

@article{HullinMatsuda2014LipidCI,
  title={Lipid compartmentalization in the endosome system.},
  author={Françoise Hullin-Matsuda and Tomohiko Taguchi and Peter Greimel and Toshihide Kobayashi},
  journal={Seminars in cell & developmental biology},
  year={2014},
  volume={31},
  pages={
          48-56
        }
}
Lipids play an essential role in the structure of the endosomal membranes as well as in their dynamic rearrangement during the transport of internalized cargoes along the endocytic pathway. In this review, we discuss the function of endosomal lipids mainly in mammalian cells, focusing on two well-known components of the lipid rafts, sphingomyelin and cholesterol, as well as on three anionic phospholipids, phosphatidylserine, polyphosphoinositides and the atypical phospholipid, bis… CONTINUE READING
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