Lipid bodies: cytoplasmic organelles important to arachidonate metabolism in macrophages and mast cells.

@article{Dvorak1983LipidBC,
  title={Lipid bodies: cytoplasmic organelles important to arachidonate metabolism in macrophages and mast cells.},
  author={Ann M. Dvorak and Harold F. Dvorak and Stephen P. Peters and E S Shulman and Donald W Macglashan and K Pyne and Veronica Harvey and Stephen J. Galli and Lawrence M. Lichtenstein},
  journal={Journal of immunology},
  year={1983},
  volume={131 6},
  pages={2965-76}
}
Much has been learned about the biochemical nature and pharmacologic activity of the products of arachidonic acid (AA) oxidation, but relatively little is known about the structures in nucleated cells into which AA is incorporated and from which it is initially mobilized. To address this question, we administered 3H-AA or other 3H-fatty acids in vitro to human lung mast cells and alveolar macrophages as well as to mouse and guinea pig peritoneal macrophages. The subcellular distribution of 3H… CONTINUE READING