Lipid-binding properties of human ApoD and Lazarillo-related lipocalins: functional implications for cell differentiation.

@article{Ruiz2013LipidbindingPO,
  title={Lipid-binding properties of human ApoD and Lazarillo-related lipocalins: functional implications for cell differentiation.},
  author={Mario Z{\'e}rega Ruiz and David Pacheco S{\'a}nchez and Colin E. Correnti and Roland K. Strong and Maria D Ganfornina},
  journal={The FEBS journal},
  year={2013},
  volume={280 16},
  pages={
          3928-43
        }
}
Lipocalins are a family of proteins characterized by a conserved eight-stranded β-barrel structure with a ligand-binding pocket. They perform a wide range of biological functions and this functional multiplicity must relate to the lipid partner involved. Apolipoprotein D (ApoD) and its insect homologues, Lazarillo (Laz) and neural Lazarillo (NLaz), share common ancestral functions like longevity, stress resistance and lipid metabolism regulation, coexisting with very specialized functions, like… CONTINUE READING
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