Lipid bilayer deposition and patterning via air bubble collapse.

  title={Lipid bilayer deposition and patterning via air bubble collapse.},
  author={Morgan D Mager and N. A. Melosh},
  journal={Langmuir : the ACS journal of surfaces and colloids},
  volume={23 18},
We report a new method for forming patterned lipid bilayers on solid substrates. In bubble collapse deposition (BCD), an air bubble is first "inked" with a monolayer of phospholipid molecules and then touched to the surface of a thermally oxidized silicon wafer and the air is slowly withdrawn. As the bubble shrinks, the lipid monolayer pressure increases. Once the monolayer exceeds the collapse pressure, it folds back on itself, depositing a stable lipid bilayer on the surface. These bilayer… CONTINUE READING