Lipid-based nanocarrier efficiently delivers highly water soluble drug across the blood–brain barrier into brain

@inproceedings{Dutta2018LipidbasedNE,
  title={Lipid-based nanocarrier efficiently delivers highly water soluble drug across the blood–brain barrier into brain},
  author={Lopamudra Dutta and Biswajit Mukherjee and Tapash Chakraborty and Malay Kumar Das and Laboni Mondal and Sanchari Bhattacharya and Raghuvir H Gaonkar and Mita C Debnath},
  booktitle={Drug delivery},
  year={2018}
}
Delivering highly water soluble drugs across blood-brain barrier (BBB) is a crucial challenge for the formulation scientists. A successful therapeutic intervention by developing a suitable drug delivery system may revolutionize treatment across BBB. Efforts were given here to unravel the capability of a newly developed fatty acid combination (stearic acid:oleic acid:palmitic acid = 8.08:4.13:1) (ML) as fundamental component of nanocarrier to deliver highly water soluble zidovudine (AZT) as a… CONTINUE READING
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