Lipid-based nano-delivery systems for skin delivery of drugs and bioactives

@inproceedings{Hua2015LipidbasedNS,
  title={Lipid-based nano-delivery systems for skin delivery of drugs and bioactives},
  author={Susan Hua},
  booktitle={Front. Pharmacol.},
  year={2015}
}
Topical drug delivery across the skin can offer many advantages, such as confer sustained drug release, lower fluctuations in plasma drug levels, circumvent first-pass metabolism, improve patient compliance, and provide local (dermal), or systemic (transdermal) effects (Schäfer-Korting et al., 2007; El Maghraby et al., 2008). However, the barrier function of the skin, exerted by the horny layer of the stratum corneum, impairs the penetration and absorption of drugs (Bouwstra and Ponec, 2006… CONTINUE READING
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