Lipid-based formulations for oral administration of poorly water-soluble drugs.

Abstract

Lipid-based drug delivery systems have shown great potentials in oral delivery of poorly water-soluble drugs, primarily for lipophilic drugs, with several successfully marketed products. Pre-dissolving drugs in lipids, surfactants, or mixtures of lipids and surfactants omits the dissolving/dissolution step, which is a potential rate limiting factor for oral… (More)
DOI: 10.1016/j.ijpharm.2013.03.054

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