Lipid and lipoprotein metabolism in Hep G2 cells.

  title={Lipid and lipoprotein metabolism in Hep G2 cells.},
  author={Sherwood R. Wang and Marcia Pessah and Jacqueline Infante and Dani{\`e}le Catala and Catherine Salvat and R. A. Jaime Infante},
  journal={Biochimica et biophysica acta},
  volume={961 3},
Lipid composition, lipid synthesis and lipoprotein secretion by the Hep G2 cell line have been studied with substrate and insulin supplied under different conditions. The lipid composition of Hep G2 cells was close to that of normal human liver, except for a higher content in sphingomyelin (P less than 0.005) and a lower phosphatidylcholine/sphingomyelin ratio. Most of the [14C]triacylglycerols secreted into the medium were recovered by ultracentrifugation at densities of 1.006 to 1.020 g/ml… CONTINUE READING
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