Lipid Signaling via Pkh1/2 Regulates Fungal CO2 Sensing through the Kinase Sch9

Abstract

Adaptation to alternating CO2 concentrations is crucial for all organisms. Carbonic anhydrases-metalloenzymes that have been found in all domains of life-enable fixation of scarce CO2 by accelerating its conversion to bicarbonate and ensure maintenance of cellular metabolism. In fungi and other eukaryotes, the carbonic anhydrase Nce103 has been shown to be… (More)
DOI: 10.1128/mBio.02211-16

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