Lipid Nanocapsules Loaded with Rhenium-188 Reduce Tumor Progression in a Rat Hepatocellular Carcinoma Model

@inproceedings{VanpouilleBox2011LipidNL,
  title={Lipid Nanocapsules Loaded with Rhenium-188 Reduce Tumor Progression in a Rat Hepatocellular Carcinoma Model},
  author={Claire Vanpouille-Box and Franck Lacoeuille and J. Roux and Christophe Aub{\'e} and Emmanuel Garcion and Nicolas Lepareur and Fr{\'e}d{\'e}ric Oberti and Francis Bouchet and Nicolas Noiret and Etienne Garin and J F Benoit and Olivier F Couturier and François Hindr{\'e}},
  booktitle={PloS one},
  year={2011}
}
BACKGROUND Due to their nanometric scale (50 nm) along with their biomimetic properties, lipid nanocapsules loaded with Rhenium-188 (LNC(188)Re-SSS) constitute a promising radiopharmaceutical carrier for hepatocellular carcinoma treatment as its size may improve tumor penetration in comparison with microspheres devices. This study was conducted to confirm the feasibility and to assess the efficacy of internal radiation with LNC(188)Re-SSS in a chemically induced hepatocellular carcinoma rat… CONTINUE READING

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