Lipid Metabolism and Cardiovascular Morbidity and Mortality in Hemodialysis Patients: Role of Factors Modulating Cytosolic Calcium.

@article{Gadallah2001LipidMA,
  title={Lipid Metabolism and Cardiovascular Morbidity and Mortality in Hemodialysis Patients: Role of Factors Modulating Cytosolic Calcium.},
  author={Merit F Gadallah and Mohamed A. El-Shahawy and George Andrews and Carlos Torres-Rivera and Dina Hanna and Marc B Blatt and Magued Ibrahim and Atef Morkos and Mohammad Abbassian and Mark Cooper},
  journal={Hemodialysis international. International Symposium on Home Hemodialysis},
  year={2001},
  volume={5 1},
  pages={59-65}
}
Animal studies indicate that insulin resistance and glucose intolerance leading to dyslipidemia in uremic rats are associated with increased cytosolic calcium ([Ca++ i]). The resistance and intolerance are reversed with verapamil, but recur after its discontinuation. This finding suggests that hyperparathyroid-induced [Ca ++ i] increase is responsible for… CONTINUE READING