Lipid A precursors protect against endotoxin challenge.

  • Ron Proctor
  • Published 1990 in Advances in experimental medicine and biology


These studies provide exciting prospects for the future treatment of gram-negative infections. The anti-endotoxin activity of lipid X, a monosaccharide precursor of lipid A, may be a prototypic compound for agents that can block the toxic effects of endotoxin that is being actively released. In contrast, monophosphoryl lipid A, a disaccharide derivative of… (More)


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