Lipase-catalyzed kinetic resolution of (±)-1-(2-furyl) ethanol in nonaqueous media.

  title={Lipase-catalyzed kinetic resolution of (±)-1-(2-furyl) ethanol in nonaqueous media.},
  author={Saravanan Devendran and Ganapati D Yadav},
  volume={26 6},
S-1-(2-Furyl) ethanol serves as an important chiral building block for the preparation of various natural products, fine chemicals, and is widely used in the chemical and pharmaceutical industries. In this work, lipase-catalyzed kinetic resolution of (R/S)-1-(2-furyl) ethanol using different acyl donors was investigated. Vinyl esters are good acyl donors vis-à-vis alkyl esters for kinetic resolution. Among them, vinyl acetate was found to be the best acyl donor. Different immobilized lipases… CONTINUE READING
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