Lipase-catalyzed kinetic resolution of aryltrimethylsilyl chiral alcohols.

Abstract

Lipase-catalyzed kinetic resolution of aryltrimethylsilyl chiral alcohols through a transesterification reaction was studied. The optimal conditions found for the kinetic resolution of m- and p-aryltrimethylsilyl chiral alcohols, led to excellent results, high conversions (c = 50%), high enantiomeric ratios (E > 200) and enantiomeric excesses for the… (More)
DOI: 10.3390/molecules16119697

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