Links between DNA methylation and nucleosome occupancy in the human genome

Abstract

DNA methylation is an epigenetic modification that is enriched in heterochromatin but depleted at active promoters and enhancers. However, the debate on whether or not DNA methylation is a reliable indicator of high nucleosome occupancy has not been settled. For example, the methylation levels of DNA flanking CTCF sites are higher in linker DNA than in… (More)
DOI: 10.1186/s13072-017-0125-5

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