Linking molecular classification of hepatocellular carcinoma and personalized medicine: preliminary steps.

@article{Villanueva2008LinkingMC,
  title={Linking molecular classification of hepatocellular carcinoma and personalized medicine: preliminary steps.},
  author={Augusto Villanueva and Sara Toffanin and Josep M Llovet},
  journal={Current opinion in oncology},
  year={2008},
  volume={20 4},
  pages={
          444-53
        }
}
PURPOSE OF REVIEW The development of high-throughput technologies able to simultaneously investigate thousands of genes (e.g. single nucleotide polymorphism-array, gene expression microarray, etc.) has opened a new era in translational research. Obtaining a molecular classification of hepatocellular carcinoma, however, remains a striking challenge. This review summarizes the molecular classifications of hepatocellular carcinoma reported so far, analyzes the status of targeted therapies tested… CONTINUE READING
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