Linking iodine with autoimmune thyroiditis.

  title={Linking iodine with autoimmune thyroiditis.},
  author={N. Rose and L. Rasooly and A. M. Saboori and C. L. Burek},
  journal={Environmental Health Perspectives},
  pages={749 - 752}
  • N. Rose, L. Rasooly, +1 author C. L. Burek
  • Published 1999
  • Medicine
  • Environmental Health Perspectives
  • A great deal of circumstantial evidence has linked iodine with the rising incidence of autoimmune thyroiditis in the United States. In our investigations, we have shown directly that T cells from humans with chronic lymphocytic thyroiditis proliferate in the presence of iodinated but not in the presence of noniodinated human thyroglobulin. Moreover, the proliferative response is restored when the thyroglobulin is iodinated artificially in vitro. Using a panel of monoclonal antibodies, we found… CONTINUE READING
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    • 4
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    • 112
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    • 158
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