Linking integrin conformation to function.


Integrins are alphabeta heterodimeric adhesion receptors that relay signals bidirectionally across the plasma membrane between the extracellular matrix and cell-surface ligands, and cytoskeletal and signalling effectors. The physical and chemical signals that are controlled by integrins are essential for intercellular communication and underpin all aspects… (More)
DOI: 10.1242/jcs.018556


2 Figures and Tables