Linking germline and somatic variation in Ewing sarcoma

  title={Linking germline and somatic variation in Ewing sarcoma},
  author={Nicholas Gomez and Ian J. Davis},
  journal={Nature Genetics},
The identification of gene-regulatory polymorphisms that influence cancer susceptibility can identify key oncogenic pathways. A new study links a germline variant to Ewing sarcoma disease susceptibility and EWSR1-FLI1–mediated gene activation. 
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