Linking binge alcohol-induced neurodamage to brain edema and potential aquaporin-4 upregulation: evidence in rat organotypic brain slice cultures and in vivo.

Abstract

Brain edema and derived oxidative stress potentially are critical events in the hippocampal-entorhinal cortical (HEC) neurodegeneration caused by binge alcohol (ethanol) intoxication and withdrawal in adult rats. Edema's role is based on findings that furosemide diuretic antagonizes binge alcohol-dependent brain overhydration and neurodamage in vivo and in… (More)
DOI: 10.1089/neu.2008.0682

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Cite this paper

@article{Sripathirathan2009LinkingBA, title={Linking binge alcohol-induced neurodamage to brain edema and potential aquaporin-4 upregulation: evidence in rat organotypic brain slice cultures and in vivo.}, author={Kumar Sripathirathan and James Brown and Edward J. Neafsey and Michael A. Collins}, journal={Journal of neurotrauma}, year={2009}, volume={26 2}, pages={261-73} }