Linking allergy to autoimmune disease.

@article{Valenta2009LinkingAT,
  title={Linking allergy to autoimmune disease.},
  author={Rudolph Valenta and Irene Mittermann and Th. Werfel and Holger Garn and Harald Renz},
  journal={Trends in immunology},
  year={2009},
  volume={30 3},
  pages={
          109-16
        }
}
Type I allergy is a classical Th2-driven hypersensitivity disease based on IgE recognition of environmental allergens. Exposure of allergic individuals to exogenous allergens leads to immediate type inflammation caused by degranulation of mast cells via IgE-allergen immune complexes and the release of inflammatory mediators, proteases and pro-inflammatory cytokines. However, allergic inflammation can occur and persist in the absence of exposure to exogenous allergens and might paradoxically… CONTINUE READING
BETA

Similar Papers

Figures, Tables, and Topics from this paper.

Citations

Publications citing this paper.
SHOWING 1-10 OF 47 CITATIONS

Molecular aspects of allergens in atopic dermatitis

  • Current opinion in allergy and clinical immunology
  • 2017
VIEW 1 EXCERPT
CITES BACKGROUND

References

Publications referenced by this paper.
SHOWING 1-10 OF 82 REFERENCES

Atopic dermatitis.

  • The New England journal of medicine
  • 2008

The IgEreactive autoantigen Hom s 2 induces damage of respiratory epithelial cells and keratinocytes via induction of IFN

W. Storm van Leeuwen
  • J . Invest . Dermatol .
  • 2008

The molecular basis of allergenicity

F 46 Shakib
  • Trends Immunol
  • 2008

increasing? Trends Immunol

R. L. Rabin, A. I. Levinson
  • Clin. Exp. Immunol
  • 2008